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CANCER CELL'S NUCLEUS IMPLANTED INSIDE AN E-NUCLEATED ZYGOTE or ZYGOTE'S NUCLEUS TRANSPLANTED INSIDE AN ENUCLEATED CANCER CELL or IMPLICATIONS?( this info within the bracket ALSO EGG CELL CAN BE CONSIDERED( added TODAY -( 05/16/2013))

Prakash Vaithyanathan Chennai, India - Brain-fu: 6153

31 Octubre 2012

 
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 The concept of Nuclear Reprogramming is well known in the academic circles of developmental biology. I asked one question to myself and i am seeking answers from all the experts in the world.

Imagine this situation - A cancer cell's nucleus is implanted inside an enucleated zygote. If the zygote succeeds in multiplication then what are the implications - a new form of organism from an evolutionary point of view or the multiplication process probably leads to the creation of cancer stem cells.  The inverse problem - what would happen if the zygote's nucleus is transplanted inside a enucleated cancer cell. Could we expect the cytoplasmic contents of the cancer cell do something to the pure zygote nucleus - What are the precise sequence of events - from a non-cancerous nucleus to cancerous one - it will obviously depend upon the cancer that we are working with. 

LIKEWISE IF WE REPLACE CANCER CELL'S NUCLEUS BY THE NUCLEUS OF EMBRYONIC STEM CELL OR INDUCED PLURIPOTENT STEM CELL - WHAT WILL BE THE IMPLICATIONS

 

// edited today - 05/16/2013 by myself: i learned that human embryonic stem cells have been obtained by cloning. i came so close but i used the word zygote in my original posting whereas the US scientists went for egg cell.  

 

Any way my question is this: what would happen if a cancer cell's nucleus is fixd inside the egg cell whose nucleus has been removed.

HEREIN LIES A POTENTIAL KNOWLEDGE MINE 

One expert from MIT wrote to me
" Nobody has tried this expt.!"

I am Prakash Vaithyanathan - a British GCE O level Science and Maths Teacher at the M.Ct.M International School chennai India - pvaithyanathan@gmail.com

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Tags: cancer cells nucleus reprogramming zygote

 

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por badfaith (Kent, United Kingdom) 9 Noviembre 2012

desde: 09/03/2010, Brain-fu: 21840

like if the cell zygote was the prism through which the new nucleus qualities shone, would the function, or "light" of that cell overall be altered by being expressed through a different prism... would the nucleus alter the function of the zygote, or the zygote alter the function of the nucleus?